| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DECR1 |
| Gene ID: | 1666 |
| Uniprot ID: | DECR_HUMAN |
| Immunogen Region: | 35-335 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 35-335 of human DECR1 (NP_001350.1). |
| Immunogen Sequence: | NTEALQSKFFSPLQKAMLPP NSFQGKVAFITGGGTGLGKG MTTLLSSLGAQCVIASRKMD VLKATAEQISSQTGNKVHAI QCDVRDPDMVQNTVSELIKV AGHPNIVINNAAGNFISPTE RLSPNAWKTITDIVLNGTAF VTLEIGKQLIKAQKGAAFLS ITTIYAETGSGFVVPSASAK AGVEAMSKSLAAEWGKYGMR FNVIQPGPIKTKGAFSRLDP TGTFEKEMIGRIPCGRLGT |
| Tissue Specificity | Heart = liver = pancreas > kidney >> skeletal muscle = lung. |
| Function | Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in mitochondria. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. |
| Protein Name | 2 -4-Dienoyl-Coa Reductase (3e-Enoyl-Coa-Producing - Mitochondrial2 -4-Dienoyl-Coa Reductase Nadph4-Enoyl-Coa Reductase NadphShort Chain Dehydrogenase/Reductase Family 18c Member 1 |
| Database Links | Reactome: R-HSA-77288 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-2 -4-Dienoyl-Coa Reductase (3e-Enoyl-Coa-Producing - Mitochondrial antibodyAnti-2 -4-Dienoyl-Coa Reductase Nadph antibodyAnti-4-Enoyl-Coa Reductase Nadph antibodyAnti-Short Chain Dehydrogenase/Reductase Family 18c Member 1 antibodyAnti-DECR1 antibodyAnti-DECR antibodyAnti-SDR18C1 antibody |
Information sourced from Uniprot.org