| Background | This gene encodes a member of the DEAD box protein family. These proteins are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD) and are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene is thought to play a role in the prognosis of patients with gastrointestinal stromal tumors. A pseudogene of this gene is present on chromosome 13. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. |
| Tissue Specificity | Detected in testis, and at lower levels in brain, kidney, lung, thymus, spleen and salivary gland. |
| Database Links | Reactome: R-HSA-159236 |
| Cellular Localisation | NucleusCytoplasmCan Translocate To The Cytoplasm In The Presence Of Mx1 |
| Protein Name | Atp-Dependent Rna Helicase Ddx39aDead Box Protein 39Nuclear Rna Helicase Urh49 |
| Alternative Names | Anti-Atp-Dependent Rna Helicase Ddx39a antibodyAnti-Dead Box Protein 39 antibodyAnti-Nuclear Rna Helicase Urh49 antibodyAnti-DDX39A antibodyAnti-DDX39 antibody |
Information sourced from uniprot.org
