| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DDX31 |
| Gene ID: | 64794 |
| Uniprot ID: | DDX31_HUMAN |
| Immunogen Region: | 652-851 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 652-851 of human DDX31 (NP_073616.6). |
| Immunogen Sequence: | EIKMEDILCVLTRDDCFKGK RWGAQKSHAVGPQEIRERAT VLQTVFEDYVHSSERRVSWA KKALQSFIQAYATYPRELKH IFHVRSLHLGHVAKSFGLRD APRNLSALTRKKRKAHVKRP DLHKKTQSKHSLAEILRSEY SSGMEADIAKVKKQNAPGEP GGRPLQHSLQPTPCFGRGKT LKWRKTQKGVQRDSKTSQKV |
| Tissue Specificity | Weakly or undetectably expressed in normal organs. Up-regulated in renal cell carcinoma. |
| Function | May have DNA helicase activity and RNA helicase activity. Probably have ssDNA and RNA dependent ATPase activity. Plays a role in ribosome biogenesis and TP53/p53 regulation through its interaction with NPM1. |
| Protein Name | Atp-Dependent Dna Helicase Ddx31Dead Box Protein 31HelicainProbable Atp-Dependent Rna Helicase Ddx31 |
| Cellular Localisation | NucleusNucleolusColocalized With Npm1 In The Nucleoli |
| Alternative Antibody Names | Anti-Atp-Dependent Dna Helicase Ddx31 antibodyAnti-Dead Box Protein 31 antibodyAnti-Helicain antibodyAnti-Probable Atp-Dependent Rna Helicase Ddx31 antibodyAnti-DDX31 antibody |
Information sourced from Uniprot.org
