Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-DCUN1D3 antibody (205-255 aa) (STJ196139)

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STJ196139
£48.00 - £252.00
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-DCN1-like protein 3 (205-255 aa) is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DCUN1D3
Gene ID: 123879
Uniprot ID: DCNL3_HUMAN
Immunogen Region: 205-255 aa
Specificity: This antibody detects endogenous levels of DCNL3 at Human/Mouse/Rat
Immunogen: Synthesized peptide derived from the human DCNL3 at the amino acid range 205-255
Function Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes and may play a role in the cell cycle progression by regulating the SCF ubiquitin E3 ligase complex, after UV damage. At the cell membrane, can promote and as well inhibit cullins neddylation.
Protein Name Dcn1-Like Protein 3
Dcnl3
Dcun1 Domain-Containing Protein 3
Defective In Cullin Neddylation Protein 1-Like Protein 3
Squamous Cell Carcinoma-Related Oncogene 3
Database Links Reactome: R-HSA-8951664
Cellular Localisation Cell Membrane
Cytoplasm
Nucleus
Perinuclear Region
After Uvc Treatment
The Protein Enters To The Nucleus Gradually
Cell Membrane Localization Is Essential For Cul3 Neddylation
Alternative Antibody Names Anti-Dcn1-Like Protein 3 antibody
Anti-Dcnl3 antibody
Anti-Dcun1 Domain-Containing Protein 3 antibody
Anti-Defective In Cullin Neddylation Protein 1-Like Protein 3 antibody
Anti-Squamous Cell Carcinoma-Related Oncogene 3 antibody
Anti-DCUN1D3 antibody
Anti-SCCRO3 antibody

Information sourced from Uniprot.org

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