| Host: |
Rabbit |
| Applications: |
WB/IHC/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DBT (11-247) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000IHC-P 1:50-1:200IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DBT |
| Gene ID: |
1629 |
| Uniprot ID: |
ODB2_HUMAN |
| Immunogen Region: |
11-247 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 11-247 of human DBT (NP_001909.3). |
| Immunogen Sequence: |
SRNAGKLICVRYFQTCGNVH VLKPNYVCFFGYPSFKYSHP HHFLKTTAALRGQVVQFKLS DIGEGIREVTVKEWYVKEGD TVSQFDSICEVQSDKASVTI TSRYDGVIKKLYYNLDDIAY VGKPLVDIETEALKDSEEDV VETPAVSHDEHTHQEIKGRK TLATPAVRRLAMENNIKLSE VVGSGKDGRILKEDILNYLE KQTGAILPPSPKVEIMPPPP KPKDMTVPILVSKPPVF |
| Function | The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). Within this complex, the catalytic function of this enzyme is to accept, and to transfer to coenzyme A, acyl groups that are generated by the branched-chain alpha-keto acid decarboxylase component. |
| Protein Name | Lipoamide Acyltransferase Component Of Branched-Chain Alpha-Keto Acid Dehydrogenase Complex - Mitochondrial52 Kda Mitochondrial Autoantigen Of Primary Biliary CirrhosisBranched Chain 2-Oxo-Acid Dehydrogenase Complex Component E2Bcoadc-E2Branched-Chain Alpha-Keto Acid Dehydrogenase Complex Component E2Bckad-E2Bckade2Dihydrolipoamide Acetyltransferase Component Of Branched-Chain Alpha-Keto Acid Dehydrogenase ComplexDihydrolipoamide Branched Chain TransacylaseDihydrolipoyllysine-Residue2-Methylpropanoyltransferase |
| Database Links | Reactome: R-HSA-389661Reactome: R-HSA-70895Reactome: R-HSA-9013407 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Lipoamide Acyltransferase Component Of Branched-Chain Alpha-Keto Acid Dehydrogenase Complex - Mitochondrial antibodyAnti-52 Kda Mitochondrial Autoantigen Of Primary Biliary Cirrhosis antibodyAnti-Branched Chain 2-Oxo-Acid Dehydrogenase Complex Component E2 antibodyAnti-Bcoadc-E2 antibodyAnti-Branched-Chain Alpha-Keto Acid Dehydrogenase Complex Component E2 antibodyAnti-Bckad-E2 antibodyAnti-Bckade2 antibodyAnti-Dihydrolipoamide Acetyltransferase Component Of Branched-Chain Alpha-Keto Acid Dehydrogenase Complex antibodyAnti-Dihydrolipoamide Branched Chain Transacylase antibodyAnti-Dihydrolipoyllysine-Residue antibodyAnti-2-Methylpropanoyltransferase antibodyAnti-DBT antibodyAnti-BCATE2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
