| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Monkey |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Protein DBF4 homolog A (10-59 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DBF4 |
| Gene ID: | 10926 |
| Uniprot ID: | DBF4A_HUMAN |
| Immunogen Region: | 10-59 aa |
| Specificity: | Dbf4 Polyclonal Antibody detects endogenous levels of Dbf4 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human DBF4 at the amino acid range 10-59 |
| Post Translational Modifications | Phosphorylation increases its interaction with PSIP1. |
| Function | Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle. |
| Protein Name | Protein Dbf4 Homolog AActivator Of S Phase KinaseChiffon Homolog ADbf4-Type Zinc Finger-Containing Protein 1 |
| Database Links | Reactome: R-HSA-176187Reactome: R-HSA-68962 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Protein Dbf4 Homolog A antibodyAnti-Activator Of S Phase Kinase antibodyAnti-Chiffon Homolog A antibodyAnti-Dbf4-Type Zinc Finger-Containing Protein 1 antibodyAnti-DBF4 antibodyAnti-ASK antibodyAnti-DBF4A antibodyAnti-ZDBF1 antibody |
Information sourced from Uniprot.org