Anti-DAZL antibody (Internal) (STJ70744)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-DAZL (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 38kDa band observed in Rat Testis lysates (calculated MW of 31.4kDa according to NP_001102884.1). This molecular weight is routinely observed by other sources. Recommended conce |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | DAZL |
| Gene ID | 1618 |
| Uniprot ID | DAZL_HUMAN |
| Accession Number | NP_001342.2 |
| Immunogen Region | Internal |
| Immunogen Sequence | GNGPQKKSVDR |
Additional Info
| Function | RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts. |
| Protein Name | Deleted In Azoospermia-LikeDaz HomologDaz-Like AutosomalDeleted In Azoospermia-Like 1Spgy-Like-Autosomal |
| Cellular Localisation | CytoplasmNucleusPredominantly CytoplasmicNuclear In Spermatogonia Until Near The End Of The Meiotic Prophase And Cytoplasmic Localization From Then Onward |
| Alternative Antibody Names | Anti-Deleted In Azoospermia-Like antibodyAnti-Daz Homolog antibodyAnti-Daz-Like Autosomal antibodyAnti-Deleted In Azoospermia-Like 1 antibodyAnti-Spgy-Like-Autosomal antibodyAnti-DAZL antibodyAnti-DAZH antibodyAnti-DAZL1 antibodyAnti-DAZLA antibodyAnti-SPGYLA antibody |
Information sourced from Uniprot.org