| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-DAPP1 (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:4000.WB: Approx 30kDa band observed in Human Kidney lysates (calculated MW of 32.0kDa according to AAF14578.1). Recommended concentration: 0.5-1µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | DAPP1 |
| Gene ID: | 27071 |
| Uniprot ID: | DAPP1_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | AAF14578.1 |
| Specificity: | This antibody was raised against the C-terminus of NP_055210.1. However, NCBI has changed the version to NP_055210.2 thus losing the C-terminal epitope. |
| Immunogen Sequence: | SALCISPEEKTDHK |
| Post Translational Modifications | Phosphorylated on tyrosine residues. |
| Function | May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K. |
| Protein Name | Dual Adapter For Phosphotyrosine And 3-Phosphotyrosine And 3-PhosphoinositideHdapp1B Lymphocyte Adapter Protein Bam32B-Cell Adapter Molecule Of 32 Kda |
| Database Links | Reactome: R-HSA-983695 |
| Cellular Localisation | CytoplasmMembranePeripheral Membrane ProteinMembrane-Associated After Cell Stimulation Leading To Its Translocation |
| Alternative Antibody Names | Anti-Dual Adapter For Phosphotyrosine And 3-Phosphotyrosine And 3-Phosphoinositide antibodyAnti-Hdapp1 antibodyAnti-B Lymphocyte Adapter Protein Bam32 antibodyAnti-B-Cell Adapter Molecule Of 32 Kda antibodyAnti-DAPP1 antibodyAnti-BAM32 antibodyAnti-HSPC066 antibody |
Information sourced from Uniprot.org