Post Translational Modifications | Hyperphosphorylation at Ser-13 occurs during the early stages of apoptosis but becomes less prominent during the later stages. Phosphorylation at Ser-13 also increases in response to stress brought on by cell injury. Proteolytically cleaved by caspases during apoptosis. Cleavage occurs at Asp-228. |
Function | Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine. |
Protein Name | Keratin - Type I Cytoskeletal 20Cytokeratin-20Ck-20Keratin-20K20Protein It |
Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Keratin - Type I Cytoskeletal 20 antibodyAnti-Cytokeratin-20 antibodyAnti-Ck-20 antibodyAnti-Keratin-20 antibodyAnti-K20 antibodyAnti-Protein It antibodyAnti-KRT20 antibody |
Information sourced from Uniprot.org