Host: | Goat |
Applications: | Pep-ELISA/WB |
Reactivity: | Human/Dog/Pig/Cow |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Goat polyclonal antibody anti-Cyclin D-type binding-protein 1 (322-333) is suitable for use in ELISA and Western Blot research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: | 0.5 mg/mL |
Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:4000.WB: Approx 40kDa band observed in Human Placenta lysates (calculated MW of 40.3kDa according to NP_036274.3). Recommended concentration: 0.3-1µg/ml. |
Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: | CCNDBP1 |
Gene ID: | 23582 |
Uniprot ID: | CCDB1_HUMAN |
Immunogen Region: | 322-333 |
Accession Number: | NP_036274.3 |
Immunogen Sequence: | TKASHVTPQPED |
Post Translational Modifications | Phosphorylated. |
Function | May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription. |
Protein Name | Cyclin-D1-Binding Protein 1Grap2 And Cyclin-D-Interacting ProteinHuman Homolog Of Maid |
Cellular Localisation | CytoplasmNucleus |
Alternative Antibody Names | Anti-Cyclin-D1-Binding Protein 1 antibodyAnti-Grap2 And Cyclin-D-Interacting Protein antibodyAnti-Human Homolog Of Maid antibodyAnti-CCNDBP1 antibodyAnti-DIP1 antibodyAnti-GCIP antibodyAnti-HHM antibody |
Information sourced from Uniprot.org