| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Cytochrome b-245 light chain alpha chain (80-160 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CYBA |
| Gene ID: | 1535 |
| Uniprot ID: | CY24A_HUMAN |
| Immunogen Region: | 80-160 aa |
| Specificity: | CY24A Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 80-160 |
| Function | Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. |
| Protein Name | Cytochrome B-245 Light ChainCytochrome B(558 Alpha ChainCytochrome B558 Subunit AlphaNeutrophil Cytochrome B 22 Kda PolypeptideSuperoxide-Generating Nadph Oxidase Light Chain SubunitP22 Phagocyte B-CytochromeP22-PhoxP22phox |
| Database Links | Reactome: R-HSA-1222556Reactome: R-HSA-1236973Reactome: R-HSA-3299685Reactome: R-HSA-4420097Reactome: R-HSA-5668599Reactome: R-HSA-6798695Reactome: R-HSA-9013149Reactome: R-HSA-9013404Reactome: R-HSA-9013423Reactome: R-HSA-9673324 |
| Cellular Localisation | Cell MembraneAs Unassembled Monomer May Localize To The Endoplasmic Reticulum |
| Alternative Antibody Names | Anti-Cytochrome B-245 Light Chain antibodyAnti-Cytochrome B(558 Alpha Chain antibodyAnti-Cytochrome B558 Subunit Alpha antibodyAnti-Neutrophil Cytochrome B 22 Kda Polypeptide antibodyAnti-Superoxide-Generating Nadph Oxidase Light Chain Subunit antibodyAnti-P22 Phagocyte B-Cytochrome antibodyAnti-P22-Phox antibodyAnti-P22phox antibodyAnti-CYBA antibody |
Information sourced from Uniprot.org
