| Short Description : | Rabbit polyclonal CXXC1 (1-210) antibody for use in WB, IP and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IP/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CXXC1 |
| Gene ID: | 30827 |
| Uniprot ID: | CXXC1_HUMAN |
| Immunogen Region: | 1-210 |
| Immunogen Sequence: | MEGDGSDPEPPDAGEDSKSE NGENAPIYCICRKPDINCFM IGCDNCNEWFHGDCIRITEK MAKAIREWYCRECREKDPKL EIRYRHKKSRERDGNERDSS EPRDEGGGRKRPVPDPDLQR RAGSGTGVGAMLARGSASPH KSSPQPLVATPSQHHQQQQQ QIKRSARMCGECEACRRTED CGHCDFCRDMKKFGGPNKIR QKCRLRQCQL |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human CXXC1 (NP_001095124.1). |
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | May be regulated by proteolysis. |
| Function | Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG. |
| Protein Name | Cxxc-Type Zinc Finger Protein 1Cpg-Binding ProteinPhd Finger And Cxxc Domain-Containing Protein 1 |
| Database Links | Reactome: R-HSA-381038Reactome: R-HSA-9772755 |
| Cellular Localisation | Nucleus SpeckleNucleusAssociated With EuchromatinDuring MitosisExcluded From Condensed Chromosomes |
| Alternative Antibody Names | Anti-Cxxc-Type Zinc Finger Protein 1 antibodyAnti-Cpg-Binding Protein antibodyAnti-Phd Finger And Cxxc Domain-Containing Protein 1 antibodyAnti-CXXC1 antibodyAnti-CFP1 antibodyAnti-CGBP antibodyAnti-PCCX1 antibodyAnti-PHF18 antibody |
Information sourced from Uniprot.org
