Anti-CXCR2 antibody (445-538) {FITC} (STJ506205)

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STJ506205-100
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Short Description :Rabbit polyclonal antibody anti-CXCR2 (445-538) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.
Applications:ELISA/IP/WB
Host:Rabbit
Reactivity:Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:FITC
Concentration:0.5-1.5 Mu g/Mu l
Purification:Affinity Purified
Dilution Range:WB: 1:500
ELISA: 1:10, 000
IP: 1:200
Formulation:Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Storage Instruction:Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol:Cxcr2
Gene ID:12765
Uniprot ID:CXCR2_MOUSE
Immunogen:Synthetic peptide corresponding to amino acids within region 445-538 on mouse C-X-C Chemokine Receptot type 2.
Immunogen Region:445-538
Post Translational Modifications Phosphorylated upon ligand binding.which is required for desensitization.
Function Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Protein Name C-X-C Chemokine Receptor Type 2
Cxc-R2
Cxcr-2
Gro/Mgsa Receptor
High Affinity Interleukin-8 Receptor B
Il-8r B
Cd Antigen Cd182
Database Links Reactome: R-MMU-380108
Reactome: -MMU-418594
Reactome: -MMU-6798695
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-C-X-C Chemokine Receptor Type 2 antibody
Anti-Cxc-R2 antibody
Anti-Cxcr-2 antibody
Anti-Gro/Mgsa Receptor antibody
Anti-High Affinity Interleukin-8 Receptor B antibody
Anti-Il-8r B antibody
Anti-Cd Antigen Cd182 antibody
Anti-Cxcr2 antibody
Anti-Cmkar2 antibody
Anti-Gpcr16 antibody
Anti-Il8rb antibody

Information sourced from Uniprot.org

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