Immunofluorescence analysis of C6 cells using GRO alpha Rabbit polyclonal antibody (STJ28366) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

Anti-CXCL1 antibody (1-107) (STJ28366)

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STJ28366
£112.50 - £524.50
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Host: Rabbit
Applications: WB/IF/ICC/ELISA
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CXCL1
Gene ID: 2919
Uniprot ID: GROA_HUMAN
Immunogen Region: 1-107
Specificity: A synthetic peptide corresponding to a sequence within amino acids 1-107 of human GRO alpha (NP_001502.1).
Immunogen Sequence: MARAALSAAPSNPRLLRVAL LLLLLVAAGRRAAGASVATE LRCQCLQTLQGIHPKNIQSV NVKSPGPHCAQTEVIATLKN GRKACLNPASPIVKKIIEKM LNSDKSN
Post Translational Modifications N-terminal processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) are produced by proteolytic cleavage after secretion from peripheral blood monocytes.
Function Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity.
Protein Name Growth-Regulated Alpha Protein
C-X-C Motif Chemokine 1
Gro-Alpha(1-73
Melanoma Growth Stimulatory Activity
Mgsa
Neutrophil-Activating Protein 3
Nap-3 Cleaved Into - Gro-Alpha(4-73 - Gro-Alpha(5-73 - Gro-Alpha(6-73
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-418594
Reactome: R-HSA-6783783
Reactome: R-HSA-6798695
Cellular Localisation Secreted
Alternative Antibody Names Anti-Growth-Regulated Alpha Protein antibody
Anti-C-X-C Motif Chemokine 1 antibody
Anti-Gro-Alpha(1-73 antibody
Anti-Melanoma Growth Stimulatory Activity antibody
Anti-Mgsa antibody
Anti-Neutrophil-Activating Protein 3 antibody
Anti-Nap-3 Cleaved Into - Gro-Alpha(4-73 - Gro-Alpha(5-73 - Gro-Alpha(6-73 antibody
Anti-CXCL1 antibody
Anti-GRO antibody
Anti-GRO1 antibody
Anti-GROA antibody
Anti-MGSA antibody
Anti-SCYB1 antibody

Information sourced from Uniprot.org

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