| Host: |
Rabbit |
| Applications: |
IHC/WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Cullin-9 (C-Term) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000IHC 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CUL9 |
| Gene ID: |
23113 |
| Uniprot ID: |
CUL9_HUMAN |
| Immunogen Region: |
C-Term |
| Specificity: |
This antibody detects endogenous levels of CUL9 at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human C-ternal CUL9 |
| Post Translational Modifications | In vitro, self-ubiquitination in the presence of E1, E2 and ubiquitin. Neddylated. |
| Function | Core component of a Cul9-RING ubiquitin-protein ligase complex, a complex that mediates ubiquitination and subsequent degradation of BIRC5 and is required to maintain microtubule dynamics and genome integrity. Acts downstream of the 3M complex, which inhibits CUL9 activity, leading to prevent ubiquitination of BIRC5. Cytoplasmic anchor protein in p53/TP53-associated protein complex. Regulates the subcellular localization of p53/TP53 and subsequent function. |
| Protein Name | Cullin-9Cul-9Ubch7-Associated Protein 1P53-Associated Parkin-Like Cytoplasmic Protein |
| Database Links | Reactome: R-HSA-8951664 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Cullin-9 antibodyAnti-Cul-9 antibodyAnti-Ubch7-Associated Protein 1 antibodyAnti-P53-Associated Parkin-Like Cytoplasmic Protein antibodyAnti-CUL9 antibodyAnti-H7AP1 antibodyAnti-KIAA0708 antibodyAnti-PARC antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
