| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CTU2 |
| Gene ID: | 348180 |
| Uniprot ID: | CTU2_HUMAN |
| Immunogen Region: | 186-515 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 186-515 of human CTU2 (NP_001012777.1). |
| Immunogen Sequence: | HVLGAGGGPGPTQGEEQPPQ PPLDPQNLARPPAPAQTEAL SQLFCSVRTLTAKEELLQTL RTHLILHMARAHGYSKVMTG DSCTRLAIKLMTNLALGRGA FLAWDTGFSDERHGDVVVVR PMRDHTLKEVAFYNRLFSVP SVFTPAVDTKAPEKASIHRL MEAFILRLQTQFPSTVSTVY RTSEKLVKGPRDGPAAGDSG PRCLLCMCALDVDAADSATA FGAQTSSRLSQMQSPIPLT |
| Function | Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. |
| Protein Name | Cytoplasmic Trna 2-Thiolation Protein 2Cytosolic Thiouridylase Subunit 2 |
| Database Links | Reactome: R-HSA-6782315 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Cytoplasmic Trna 2-Thiolation Protein 2 antibodyAnti-Cytosolic Thiouridylase Subunit 2 antibodyAnti-CTU2 antibodyAnti-C16orf84 antibodyAnti-NCS2 antibody |
Information sourced from Uniprot.org