Anti-CTSS antibody (115-331) (STJ23285)

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STJ23285
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Short Description :Rabbit polyclonal CTSS (115-331) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IF/ICC/ELISA
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:500-1:1000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:CTSS
Gene ID:1520
Uniprot ID:CATS_HUMAN
Immunogen Region:115-331
Immunogen Sequence:LPDSVDWREKGCVTEVKYQG SCGACWAFSAVGALEAQLKL KTGKLVSLSAQNLVDCSTEK YGNKGCNGGFMTTAFQYIID NKGIDSDASYPYKAMDQKCQ YDSKYRAATCSKYTELPYGR EDVLKEAVANKGPVSVGVDA RHPSFFLYRSGVYYEPSCTQ NVNHGVLVVGYGDLNGKEYW LVKNSWGHNFGEEGYIRMAR NKGNHCGIASFPSYPEI
Specificity:Recombinant fusion protein containing a sequence corresponding to amino acids 115-331 of human CTSS (NP_004070.3).
Function Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules and MHC class II antigen presentation. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L.
Protein Name Cathepsin S
Database Links Reactome: R-HSA-1236977
Reactome: R-HSA-1474228
Reactome: R-HSA-1679131
Reactome: R-HSA-2022090
Reactome: R-HSA-2132295
Reactome: R-HSA-6798695
Cellular Localisation Lysosome
Secreted
Cytoplasmic Vesicle
Phagosome
Alternative Antibody Names Anti-Cathepsin S antibody
Anti-CTSS antibody

Information sourced from Uniprot.org