Anti-CTSS antibody (115-331) (STJ115443)

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STJ115443
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Host: Rabbit
Applications: WB/IHC-P/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
IHC-P:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CTSS
Gene ID: 1520
Uniprot ID: CATS_HUMAN
Immunogen Region: 115-331
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 115-331 of human CTSS (NP_004070.3).
Immunogen Sequence: LPDSVDWREKGCVTEVKYQG SCGACWAFSAVGALEAQLKL KTGKLVSLSAQNLVDCSTEK YGNKGCNGGFMTTAFQYIID NKGIDSDASYPYKAMDQKCQ YDSKYRAATCSKYTELPYGR EDVLKEAVANKGPVSVGVDA RHPSFFLYRSGVYYEPSCTQ NVNHGVLVVGYGDLNGKEYW LVKNSWGHNFGEEGYIRMAR NKGNHCGIASFPSYPEI
Function Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules and MHC class II antigen presentation. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L.
Protein Name Cathepsin S
Database Links Reactome: R-HSA-1236977
Reactome: R-HSA-1474228
Reactome: R-HSA-1679131
Reactome: R-HSA-2022090
Reactome: R-HSA-2132295
Reactome: R-HSA-6798695
Cellular Localisation Lysosome
Secreted
Cytoplasmic Vesicle
Phagosome
Alternative Antibody Names Anti-Cathepsin S antibody
Anti-CTSS antibody

Information sourced from Uniprot.org