| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CTSA |
| Gene ID: | 5476 |
| Uniprot ID: | PPGB_HUMAN |
| Immunogen Region: | 210-450 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 210-450 of human CTSA (NP_001121167.1). |
| Immunogen Sequence: | SYEQNDNSLVYFAYYHGLLG NRLWSSLQTHCCSQNKCNFY DNKDLECVTNLQEVARIVGN SGLNIYNLYAPCAGGVPSHF RYEKDTVVVQDLGNIFTRLP LKRMWHQALLRSGDKVRMDP PCTNTTAASTYLNNPYVRKA LNIPEQLPQWDMCNFLVNLQ YRRLYRSMNSQYLKLLSSQK YQILLYNGDVDMACNFMGDE WFVDSLNQKMEVQRRPWLVK YGDSGEQIAGFVKEFSHIA |
| Function | Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins. |
| Protein Name | Lysosomal Protective ProteinCarboxypeptidase CCarboxypeptidase LCathepsin AProtective Protein Cathepsin APpcaProtective Protein For Beta-Galactosidase Cleaved Into - Lysosomal Protective Protein 32 Kda Chain - Lysosomal Protective Protein 20 Kda Chain |
| Database Links | Reactome: R-HSA-2132295Reactome: R-HSA-4085001Reactome: R-HSA-4341670Reactome: R-HSA-6798695Reactome: R-HSA-9840310 |
| Cellular Localisation | Lysosome |
| Alternative Antibody Names | Anti-Lysosomal Protective Protein antibodyAnti-Carboxypeptidase C antibodyAnti-Carboxypeptidase L antibodyAnti-Cathepsin A antibodyAnti-Protective Protein Cathepsin A antibodyAnti-Ppca antibodyAnti-Protective Protein For Beta-Galactosidase Cleaved Into - Lysosomal Protective Protein 32 Kda Chain - Lysosomal Protective Protein 20 Kda Chain antibodyAnti-CTSA antibodyAnti-PPGB antibody |
Information sourced from Uniprot.org
