| Host: |
Goat |
| Applications: |
Pep-ELISA/IF/FC |
| Reactivity: |
Human/Dog |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-CTDSPL (Internal) is suitable for use in ELISA, Immunofluorescence and Flow Cytometry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
Peptide ELISA: antibody detection limit dilution 1:32000.WB: Preliminary testing showed a band at approx 28kDa in nuclear lysate of cell lines A431 and HeLa, after 1-2µg/ml antibody staining (calculated Mwt of 29.9kDa according to NP_005799.2). |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
CTDSPL |
| Gene ID: |
10217 |
| Uniprot ID: |
CTDSL_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_001008393.1; NP_005799.2 |
| Specificity: |
This antibody is expected to recognise both isoforms (NP_001008393.1; NP_005799.2). |
| Immunogen Sequence: |
QCNVSLKKQRSRS |
| Function | Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. |
| Protein Name | Ctd Small Phosphatase-Like ProteinCtdsp-LikeCarboxy-Terminal Domain Rna Polymerase Ii Polypeptide A Small Phosphatase 3Nif-Like ProteinNuclear Lim Interactor-Interacting Factor 1Nli-Interacting Factor 1Protein Ya22Hya22Rbsp3Small C-Terminal Domain Phosphatase 3Scp3Small Ctd Phosphatase 3 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Ctd Small Phosphatase-Like Protein antibodyAnti-Ctdsp-Like antibodyAnti-Carboxy-Terminal Domain Rna Polymerase Ii Polypeptide A Small Phosphatase 3 antibodyAnti-Nif-Like Protein antibodyAnti-Nuclear Lim Interactor-Interacting Factor 1 antibodyAnti-Nli-Interacting Factor 1 antibodyAnti-Protein Ya22 antibodyAnti-Hya22 antibodyAnti-Rbsp3 antibodyAnti-Small C-Terminal Domain Phosphatase 3 antibodyAnti-Scp3 antibodyAnti-Small Ctd Phosphatase 3 antibodyAnti-CTDSPL antibodyAnti-C3orf8 antibodyAnti-NIF1 antibodyAnti-NIFL antibodyAnti-SCP3 antibodyAnti-YA22 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
