| Function | Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. |
| Protein Name | Ctd Small Phosphatase-Like ProteinCtdsp-LikeCarboxy-Terminal Domain Rna Polymerase Ii Polypeptide A Small Phosphatase 3Nif-Like ProteinNuclear Lim Interactor-Interacting Factor 1Nli-Interacting Factor 1Protein Ya22Hya22Rbsp3Small C-Terminal Domain Phosphatase 3Scp3Small Ctd Phosphatase 3 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Ctd Small Phosphatase-Like Protein antibodyAnti-Ctdsp-Like antibodyAnti-Carboxy-Terminal Domain Rna Polymerase Ii Polypeptide A Small Phosphatase 3 antibodyAnti-Nif-Like Protein antibodyAnti-Nuclear Lim Interactor-Interacting Factor 1 antibodyAnti-Nli-Interacting Factor 1 antibodyAnti-Protein Ya22 antibodyAnti-Hya22 antibodyAnti-Rbsp3 antibodyAnti-Small C-Terminal Domain Phosphatase 3 antibodyAnti-Scp3 antibodyAnti-Small Ctd Phosphatase 3 antibodyAnti-CTDSPL antibodyAnti-C3orf8 antibodyAnti-NIF1 antibodyAnti-NIFL antibodyAnti-SCP3 antibodyAnti-YA22 antibody |
Information sourced from Uniprot.org
