| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (1-50 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CTDSP1 |
| Gene ID: | 58190 |
| Uniprot ID: | CTDS1_HUMAN |
| Immunogen Region: | 1-50 aa |
| Specificity: | CTDSP1 Polyclonal Antibody detects endogenous levels of CTDSP1 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human CTDSP1 at the amino acid range 1-50 |
| Function | Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. |
| Protein Name | Carboxy-Terminal Domain Rna Polymerase Ii Polypeptide A Small Phosphatase 1Nuclear Lim Interactor-Interacting Factor 3Nli-IfNli-Interacting Factor 3Small C-Terminal Domain Phosphatase 1Scp1Small Ctd Phosphatase 1 |
| Cellular Localisation | NucleusColocalizes With Rna Polymerase Ii |
| Alternative Antibody Names | Anti-Carboxy-Terminal Domain Rna Polymerase Ii Polypeptide A Small Phosphatase 1 antibodyAnti-Nuclear Lim Interactor-Interacting Factor 3 antibodyAnti-Nli-If antibodyAnti-Nli-Interacting Factor 3 antibodyAnti-Small C-Terminal Domain Phosphatase 1 antibodyAnti-Scp1 antibodyAnti-Small Ctd Phosphatase 1 antibodyAnti-CTDSP1 antibodyAnti-NIF3 antibodyAnti-NLIIF antibodyAnti-SCP1 antibody |
Information sourced from Uniprot.org