Anti-CtBP1 antibody (1-440aa) [AT4D6] (STJA0041602)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2bk
ImmunogenRecombinant human CTBP1 (1-440aa) purified from E. coli
General Information
| Short Description | Mouse monoclonal anti-CtBP1 (1-440aa) for use in ELISA, WB, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB/ICC/IF |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | AT4D6 |
| Isotype | IgG2bk |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | By protein-G affinity chromatography |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CTBP1 |
| Gene ID | 1487 |
| Uniprot ID | CTBP1_HUMAN |
| Accession Number | NP_001319 |
| Immunogen | Recombinant human CTBP1 (1-440aa) purified from E. coli |
| Immunogen Region | 1-440aa |
Additional Info
| Tissue Specificity | Expressed in germinal center B-cells. |
| Post Translational Modifications | The level of phosphorylation appears to be regulated during the cell cycle. Phosphorylation by HIPK2 on Ser-422 induces proteasomal degradation. ADP-ribosylated.when cells are exposed to brefeldin A. Sumoylation on Lys-428 is promoted by the E3 SUMO-protein ligase CBX4. |
| Function | Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. |
| Protein Name | C-Terminal-Binding Protein 1Ctbp1 |
| Database Links | Reactome: R-HSA-3769402Reactome: R-HSA-3899300Reactome: R-HSA-4641265Reactome: R-HSA-5339700 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-C-Terminal-Binding Protein 1 antibodyAnti-Ctbp1 antibodyAnti-CTBP1 antibodyAnti-CTBP antibody |
Information sourced from Uniprot.org