Western blot analysis of extracts of various cell lines, using CSF3R antibody (STJ29974) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-CSF3R antibody (650-750) (STJ29974)

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STJ29974
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CSF3R
Gene ID: 1441
Uniprot ID: CSF3R_HUMAN
Immunogen Region: 650-750
Specificity: A synthetic peptide corresponding to a sequence within amino acids 650-750 of human CSF3R (NP_000751.1).
Immunogen Sequence: CSPNRKNPLWPSVPDPAHSS LGSWVPTIMEEDAFQLPGLG TPPITKLTVLEEDEKKPVPW ESHNSSETCGLPTLVQTYVL QGDPRAVSTQPQSQSGTSDQ V
Tissue Specificity One or several isoforms have been found in myelogenous leukemia cell line KG-1, leukemia U-937 cell line, in bone marrow cells, placenta, and peripheral blood granulocytes. Isoform GCSFR-2 is found only in leukemia U-937 cells. Isoform GCSFR-3 is highly expressed in placenta.
Post Translational Modifications N-glycosylated.
Function Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differentiation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface.
Protein Name Granulocyte Colony-Stimulating Factor Receptor
G-Csf Receptor
G-Csf-R
Cd Antigen Cd114
Database Links Reactome: R-HSA-449836
Reactome: R-HSA-9616222
Reactome: R-HSA-9674555
Reactome: R-HSA-9705462
Cellular Localisation Isoform 2: Secreted
Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Granulocyte Colony-Stimulating Factor Receptor antibody
Anti-G-Csf Receptor antibody
Anti-G-Csf-R antibody
Anti-Cd Antigen Cd114 antibody
Anti-CSF3R antibody
Anti-GCSFR antibody

Information sourced from Uniprot.org

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