Anti-CRP antibody (100-200) (STJ23230)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CRP (100-200) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CRP |
| Gene ID | 1401 |
| Uniprot ID | CRP_HUMAN |
| Immunogen Region | 100-200 |
| Immunogen Sequence | ILFEVPEVTVAPVHICTSWE SASGIVEFWVDGKPRVRKSL KKGYTVGAEASIILGQEQDS FGGNFEGSQSLVGDIGNVNM WDFVLSPDEINTIYLGGPFS P |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human C-Reactive Protein (CRP) (NP_000558.2). |
Additional Info
| Tissue Specificity | Found in plasma. |
| Function | Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. |
| Protein Name | C-Reactive Protein Cleaved Into - C-Reactive Protein(1-205 |
| Database Links | Reactome: R-HSA-173623 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-C-Reactive Protein Cleaved Into - C-Reactive Protein(1-205 antibodyAnti-CRP antibodyAnti-PTX1 antibody |
Information sourced from Uniprot.org