Host: |
Rabbit |
Applications: |
WB/IF |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-CRABP2 (22-94) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000IF/ICC 1:20-1:100 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
CRABP2 |
Gene ID: |
1382 |
Uniprot ID: |
RABP2_HUMAN |
Immunogen Region: |
22-94 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 22-94 of human CRABP2 (NP_001869.1). |
Immunogen Sequence: |
VLGVNVMLRKIAVAAASKPA VEIKQEGDTFYIKTSTTVRT TEINFKVGEEFEEQTVDGRP CKSLVKWESENKM |
Post Translational Modifications | Sumoylated in response to retinoic acid binding, sumoylation is critical for dissociation from ER and subsequent nuclear translocation. |
Function | Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors. |
Protein Name | Cellular Retinoic Acid-Binding Protein 2Cellular Retinoic Acid-Binding Protein IiCrabp-Ii |
Database Links | Reactome: R-HSA-5362517 |
Cellular Localisation | CytoplasmEndoplasmic ReticulumNucleusUpon Ligand BindingA Conformation Change Exposes A Nuclear Localization Motif And The Protein Is Transported Into The Nucleus |
Alternative Antibody Names | Anti-Cellular Retinoic Acid-Binding Protein 2 antibodyAnti-Cellular Retinoic Acid-Binding Protein Ii antibodyAnti-Crabp-Ii antibodyAnti-CRABP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance