| Host: | Mouse |
| Applications: | ELISA/WB/ICC/IF |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-CRABP2 (1-138aa) for use in ELISA, WB, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | AT2E11 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2ak |
| Formulation: | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Purification: | By protein-G affinity chromatography |
| Concentration: | 1 mg/mL |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CRABP2 |
| Gene ID: | 1382 |
| Uniprot ID: | RABP2_HUMAN |
| Immunogen Region: | 1-138aa |
| Accession Number: | NP_001869 |
| Immunogen: | Recombinant human CRABP2 (1-138aa) purified from E. coli |
| Post Translational Modifications | Sumoylated in response to retinoic acid binding, sumoylation is critical for dissociation from ER and subsequent nuclear translocation. |
| Function | Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors. |
| Protein Name | Cellular Retinoic Acid-Binding Protein 2Cellular Retinoic Acid-Binding Protein IiCrabp-Ii |
| Database Links | Reactome: R-HSA-5362517 |
| Cellular Localisation | CytoplasmEndoplasmic ReticulumNucleusUpon Ligand BindingA Conformation Change Exposes A Nuclear Localization Motif And The Protein Is Transported Into The Nucleus |
| Alternative Antibody Names | Anti-Cellular Retinoic Acid-Binding Protein 2 antibodyAnti-Cellular Retinoic Acid-Binding Protein Ii antibodyAnti-Crabp-Ii antibodyAnti-CRABP2 antibody |
Information sourced from Uniprot.org