| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:100-1:500IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CPT1B |
| Gene ID: | 1375 |
| Uniprot ID: | CPT1B_HUMAN |
| Immunogen Region: | 533-772 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 533-772 of human CPT1B (NP_004368.1). |
| Immunogen Sequence: | SYQVAKALADDVELYCFQFL PFGKGLIKKCRTSPDAFVQI ALQLAHFRDRGKFCLTYEAS MTRMFREGRTETVRSCTSES TAFVQAMMEGSHTKADLRDL FQKAAKKHQNMYRLAMTGAG IDRHLFCLYLVSKYLGVSSP FLAEVLSEPWRLSTSQIPQS QIRMFDPEQHPNHLGAGGGF GPVADDGYGVSYMIAGENTI FFHISSKFSSSETNAQRFGN HIRKALLDIADLFQVPKAY |
| Tissue Specificity | Strong expression in heart and skeletal muscle. No expression in liver and kidney. |
| Function | Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. |
| Protein Name | Carnitine O-Palmitoyltransferase 1 - Muscle IsoformCpt1-MCarnitine O-Palmitoyltransferase I - Muscle IsoformCpt ICpti-MCarnitine Palmitoyltransferase 1bCarnitine Palmitoyltransferase I-Like Protein |
| Database Links | Reactome: R-HSA-200425Reactome: R-HSA-5362517 |
| Cellular Localisation | Mitochondrion Outer MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Carnitine O-Palmitoyltransferase 1 - Muscle Isoform antibodyAnti-Cpt1-M antibodyAnti-Carnitine O-Palmitoyltransferase I - Muscle Isoform antibodyAnti-Cpt I antibodyAnti-Cpti-M antibodyAnti-Carnitine Palmitoyltransferase 1b antibodyAnti-Carnitine Palmitoyltransferase I-Like Protein antibodyAnti-CPT1B antibodyAnti-KIAA1670 antibody |
Information sourced from Uniprot.org