| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-Carnitine O-Palmitoyltransferase 1-Liver Isoform (520-720) is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S4846RM |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CPT1A |
| Gene ID: |
1374 |
| Uniprot ID: |
CPT1A_HUMAN |
| Immunogen Region: |
520-720 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 520-720 of human CPT1A (NP_001867.2). |
| Immunogen Sequence: |
WDIPGECQEVIETSLNTANL LANDVDFHSFPFVAFGKGII KKCRTSPDAFVQLALQLAHY KDMGKFCLTYEASMTRLFRE GRTETVRSCTTESCDFVRAM VDPAQTVEQRLKLFKLASEK HQHMYRLAMTGSGIDRHLFC LYVVSKYLAVESPFLKEVLS EPWRLSTSQTPQQQVELFDL ENNPEYVSSGGGFGPVADDG Y |
| Tissue Specificity | Strong expression in kidney and heart, and lower in liver and skeletal muscle. |
| Function | Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Plays an important role in hepatic triglyceride metabolism. |
| Protein Name | Carnitine O-Palmitoyltransferase 1 - Liver IsoformCpt1-LCarnitine O-Palmitoyltransferase I - Liver IsoformCpt ICpti-LCarnitine Palmitoyltransferase 1a |
| Database Links | Reactome: R-HSA-1368082Reactome: R-HSA-1989781Reactome: R-HSA-200425Reactome: R-HSA-5362517 |
| Cellular Localisation | Mitochondrion Outer MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Carnitine O-Palmitoyltransferase 1 - Liver Isoform antibodyAnti-Cpt1-L antibodyAnti-Carnitine O-Palmitoyltransferase I - Liver Isoform antibodyAnti-Cpt I antibodyAnti-Cpti-L antibodyAnti-Carnitine Palmitoyltransferase 1a antibodyAnti-CPT1A antibodyAnti-CPT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
