| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CPOX |
| Gene ID: | 1371 |
| Uniprot ID: | HEM6_HUMAN |
| Immunogen Region: | 111-454 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 111-454 of human CPOX (NP_000088.3). |
| Immunogen Sequence: | TSLGRPEEEEDELAHRCSSF MAPPVTDLGELRRRPGDMKT KMELLILETQAQVCQALAQV DGGANFSVDRWERKEGGGGI SCVLQDGCVFEKAGVSISVV HGNLSEEAAKQMRSRGKVLK TKDGKLPFCAMGVSSVIHPK NPHAPTIHFNYRYFEVEEAD GNKQWWFGGGCDLTPTYLNQ EDAVHFHRTLKEACDQHGPD LYPKFKKWCDDYFFIAHRGE RRGIGGIFFDDLDSPSKEE |
| Function | Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX and participates to the sixth step in the heme biosynthetic pathway. |
| Protein Name | Oxygen-Dependent Coproporphyrinogen-Iii Oxidase - Mitochondrial Cox Coprogen Oxidase Coproporphyrinogenase |
| Database Links | Reactome: R-HSA-189451 |
| Cellular Localisation | Mitochondrion Intermembrane Space |
| Alternative Antibody Names | Anti-Oxygen-Dependent Coproporphyrinogen-Iii Oxidase - Mitochondrial antibody Anti-Cox antibody Anti-Coprogen Oxidase antibody Anti-Coproporphyrinogenase antibody Anti-CPOX antibody Anti-CPO antibody Anti-CPX antibody |
Information sourced from Uniprot.org