Anti-CPOX antibody (111-454) (STJ23214)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ23214
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General Information

Short DescriptionRabbit polyclonal CPOX (111-454) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolCPOX
Gene ID1371
Uniprot IDHEM6_HUMAN
Immunogen Region111-454
Immunogen SequenceTSLGRPEEEEDELAHRCSSF MAPPVTDLGELRRRPGDMKT KMELLILETQAQVCQALAQV DGGANFSVDRWERKEGGGGI SCVLQDGCVFEKAGVSISVV HGNLSEEAAKQMRSRGKVLK TKDGKLPFCAMGVSSVIHPK NPHAPTIHFNYRYFEVEEAD GNKQWWFGGGCDLTPTYLNQ EDAVHFHRTLKEACDQHGPD LYPKFKKWCDDYFFIAHRGE RRGIGGIFFDDLDSPSKEE
SpecificityRecombinant fusion protein containing a sequence corresponding to amino acids 111-454 of human CPOX (NP_000088.3).

Additional Info

Function Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX and participates to the sixth step in the heme biosynthetic pathway.
Protein Name Oxygen-Dependent Coproporphyrinogen-Iii Oxidase - Mitochondrial
Cox
Coprogen Oxidase
Coproporphyrinogenase
Database Links Reactome: R-HSA-189451
Cellular Localisation Mitochondrion Intermembrane Space
Alternative Antibody Names Anti-Oxygen-Dependent Coproporphyrinogen-Iii Oxidase - Mitochondrial antibody
Anti-Cox antibody
Anti-Coprogen Oxidase antibody
Anti-Coproporphyrinogenase antibody
Anti-CPOX antibody
Anti-CPO antibody
Anti-CPX antibody

Information sourced from Uniprot.org

Citations

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