Anti-Collagen IV antibody [SRM14864] (STJ11109594)

SKU:
STJ11109594
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Host: Rabbit
Applications: WB/IF/ICC/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Monoclonal
Clone ID : SRM14864
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity purification
Dilution Range: WB, 1:1000-1:3000
IF/ICC, 1:50-1:200
ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: COL4A1
COL4A3
1282
1285
1284
CO4A1_HUMAN
CO4A3_HUMAN
CO4A2_HUMAN
Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tissue Specificity P02462 - Highly expressed in placenta.
Q01955 - Alpha 3 and alpha 4 type IV collagens are colocalized and present in kidney, eye, basement membranes of lens capsule, cochlea, lung, skeletal muscle, aorta, synaptic fibers, fetal kidney and fetal lung. PubMed:8083201 reports similar levels of expression of alpha 3 and alpha 4 type IV collagens in kidney, but PubMed:7523402 reports that in kidney levels of alpha 3 type IV collagen are significantly lower than those of alpha 4 type IV collagen. alpha 3 type IV collagen is not detected in heart, brain, placenta, liver, pancreas, extrasynaptic muscle fibers, endoneurial and perineurial nerves, fetal brain, fetal heart and fetal liver. alpha 3 type IV collagen is strongly expressed in pancreas, neuroretina and calvaria and not expressed in adrenal, ileum and skin. Isoform 1 and isoform 3 are strongly expressed in kidney, lung, suprarenal capsule, muscle and spleen, in each of these tissues isoform 1 is more abundant than isoform 3. Isoform 1 and isoform 3 are expressed at low levels in artery, fat, pericardium and peripherical nerve, but not in placenta, mesangium, skin, pleura and cultured umbilical endothelial cells.
P08572 - NA
P29400 - Isoform 2 is found in kidney.
P02462 - Highly expressed in placenta.
Q01955 - Alpha 3 and alpha 4 type IV collagens are colocalized and present in kidney, eye, basement membranes of lens capsule, cochlea, lung, skeletal muscle, aorta, synaptic fibers, fetal kidney and fetal lung. PubMed:8083201 reports similar levels of expression of alpha 3 and alpha 4 type IV collagens in kidney, but PubMed:7523402 reports that in kidney levels of alpha 3 type IV collagen are significantly lower than those of alpha 4 type IV collagen. alpha 3 type IV collagen is not detected in heart, brain, placenta, liver, pancreas, extrasynaptic muscle fibers, endoneurial and perineurial nerves, fetal brain, fetal heart and fetal liver. alpha 3 type IV collagen is strongly expressed in pancreas, neuroretina and calvaria and not expressed in adrenal, ileum and skin. Isoform 1 and isoform 3 are strongly expressed in kidney, lung, suprarenal capsule, muscle and spleen, in each of these tissues isoform 1 is more abundant than isoform 3. Isoform 1 and isoform 3 are expressed at low levels in artery, fat, pericardium and peripherical nerve, but not in placenta, mesangium, skin, pleura and cultured umbilical endothelial cells.
P08572 - NA
P29400 - Isoform 2 is found in kidney.
P02462 - Highly expressed in placenta.
Q01955 - Alpha 3 and alpha 4 type IV collagens are colocalized and present in kidney, eye, basement membranes of lens capsule, cochlea, lung, skeletal muscle, aorta, synaptic fibers, fetal kidney and fetal lung. PubMed:8083201 reports similar levels of expression of alpha 3 and alpha 4 type IV collagens in kidney, but PubMed:7523402 reports that in kidney levels of alpha 3 type IV collagen are significantly lower than those of alpha 4 type IV collagen. alpha 3 type IV collagen is not detected in heart, brain, placenta, liver, pancreas, extrasynaptic muscle fibers, endoneurial and perineurial nerves, fetal brain, fetal heart and fetal liver. alpha 3 type IV collagen is strongly expressed in pancreas, neuroretina and calvaria and not expressed in adrenal, ileum and skin. Isoform 1 and isoform 3 are strongly expressed in kidney, lung, suprarenal capsule, muscle and spleen, in each of these tissues isoform 1 is more abundant than isoform 3. Isoform 1 and isoform 3 are expressed at low levels in artery, fat, pericardium and peripherical nerve, but not in placenta, mesangium, skin, pleura and cultured umbilical endothelial cells.
P08572 - NA
P29400 - Isoform 2 is found in kidney.
Alternative Antibody Names Anti-Collagen Alpha-1(Iv Chain Cleaved Into - Arresten antibody
Anti-COL4A1 antibody
Anti-Collagen Alpha-3(Iv Chain antibody
Anti-Goodpasture Antigen Cleaved Into - Tumstatin antibody
Anti-COL4A3 antibody
Anti-Collagen Alpha-2(Iv Chain Cleaved Into - Canstatin antibody
Anti-COL4A2 antibody
Anti-Collagen Alpha-5(Iv Chain antibody
Anti-COL4A5 antibody
Anti-Collagen Alpha-1(Iv Chain Cleaved Into - Arresten antibody
Anti-COL4A1 antibody
Anti-Collagen Alpha-3(Iv Chain antibody
Anti-Goodpasture Antigen Cleaved Into - Tumstatin antibody
Anti-COL4A3 antibody
Anti-Collagen Alpha-2(Iv Chain Cleaved Into - Canstatin antibody
Anti-COL4A2 antibody
Anti-Collagen Alpha-5(Iv Chain antibody
Anti-COL4A5 antibody
Anti-Collagen Alpha-1(Iv Chain Cleaved Into - Arresten antibody
Anti-COL4A1 antibody
Anti-Collagen Alpha-3(Iv Chain antibody
Anti-Goodpasture Antigen Cleaved Into - Tumstatin antibody
Anti-COL4A3 antibody
Anti-Collagen Alpha-2(Iv Chain Cleaved Into - Canstatin antibody
Anti-COL4A2 antibody
Anti-Collagen Alpha-5(Iv Chain antibody
Anti-COL4A5 antibody

Information sourced from Uniprot.org