Anti-Coactosin-like Protein 1/COTL1 antibody (1-142aa) [AT1D6] (STJA0041688)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2bk
ImmunogenRecombinant human COTL1 (1-142aa) purified from E. coli
General Information
| Short Description | Mouse monoclonal anti-Coactosin-like Protein 1/COTL1 (1-142aa) for use in ELISA, WB and FACS in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB/FACS |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | AT1D6 |
| Isotype | IgG2bk |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | By protein-A affinity chromatography |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | COTL1 |
| Gene ID | 23406 |
| Uniprot ID | COTL1_HUMAN |
| Accession Number | NP_066972 |
| Immunogen | Recombinant human COTL1 (1-142aa) purified from E. coli |
| Immunogen Region | 1-142aa |
Additional Info
| Tissue Specificity | Widely expressed with highest levels in placenta, lung, kidney and peripheral blood leukocytes and lower levels in brain, liver and pancreas. |
| Function | Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5 (5LO), influencing both its stability and activity in leukotrienes synthesis. |
| Protein Name | Coactosin-Like Protein |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | CytoplasmCytoskeletonNucleus |
| Alternative Antibody Names | Anti-Coactosin-Like Protein antibodyAnti-COTL1 antibodyAnti-CLP antibody |
Information sourced from Uniprot.org