• Western blot analysis of various lysates using CNTN6 Rabbit polyclonal antibody (STJ116487) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 60s.

Anti-CNTN6 antibody (20-110) (STJ116487)

SKU:
STJ116487

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CNTN6 (20-110) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CNTN6
Gene ID: 27255
Uniprot ID: CNTN6_HUMAN
Immunogen Region: 20-110
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-110 of human CNTN6 (NP_055276.1).
Immunogen Sequence: DGLLSRPIFTQEPHDVIFPL DLSKSEVILNCAANGYPSPH YRWKQNGTDIDFTMSYHYRL DGGSLAINSPHTDQDIGMYQ CLATNLLGTIL
Tissue Specificity Expressed in nervous system. Highly expressed in cerebellum. Expressed at intermediate level in thalamus, subthalamic nucleus. Weakly expressed in corpus callosum, caudate nucleus and spinal cord.
Function Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination.
Protein Name Contactin-6
Neural Recognition Molecule Nb-3
Hnb-3
Database Links Reactome: R-HSA-447041
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Alternative Antibody Names Anti-Contactin-6 antibody
Anti-Neural Recognition Molecule Nb-3 antibody
Anti-Hnb-3 antibody
Anti-CNTN6 antibody

Information sourced from Uniprot.org

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