| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CNTN6 (20-110) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CNTN6 |
| Gene ID: |
27255 |
| Uniprot ID: |
CNTN6_HUMAN |
| Immunogen Region: |
20-110 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 20-110 of human CNTN6 (NP_055276.1). |
| Immunogen Sequence: |
DGLLSRPIFTQEPHDVIFPL DLSKSEVILNCAANGYPSPH YRWKQNGTDIDFTMSYHYRL DGGSLAINSPHTDQDIGMYQ CLATNLLGTIL |
| Tissue Specificity | Expressed in nervous system. Highly expressed in cerebellum. Expressed at intermediate level in thalamus, subthalamic nucleus. Weakly expressed in corpus callosum, caudate nucleus and spinal cord. |
| Function | Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination. |
| Protein Name | Contactin-6Neural Recognition Molecule Nb-3Hnb-3 |
| Database Links | Reactome: R-HSA-447041 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Contactin-6 antibodyAnti-Neural Recognition Molecule Nb-3 antibodyAnti-Hnb-3 antibodyAnti-CNTN6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
