| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CNTN4 |
| Gene ID: | 152330 |
| Uniprot ID: | CNTN4_HUMAN |
| Immunogen Region: | 448-697 |
| Immunogen Sequence: | VGVFNNKGEGPFSPTTVVYS AEEEPTKPPASIFARSLSAT DIEVFWASPLEKNRGRIQGY EVKYWRHEDKEENARKIRTV GNQTSTKITNLKGSVLYHLA VKAYNSAGTGPSSATVNVTT RKPPPSQPPGNIIWNSSDSK IILNWDQVKALDNESEVKGY KVLYRWNRQSSTSVIETNKT SVELSLPFDEDYIIEIKPFS DGGDGSSSEQIRIPKISNAY ARGSGASTSNACTLSAIST |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 448-697 of human CNTN4 (NP_001193885.1). |
| Tissue Specificity | Mainly expressed in brain. Highly expressed in cerebellum and weakly expressed in corpus callosum, caudate nucleus, amygdala and spinal cord. Also expressed in testis, pancreas, thyroid, uterus, small intestine and kidney. Not expressed in skeletal muscle. Isoform 2 is weakly expressed in cerebral cortex. |
| Function | Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity. May be involved in synaptogenesis. |
| Protein Name | Contactin-4Brain-Derived Immunoglobulin Superfamily Protein 2Big-2 |
| Database Links | Reactome: R-HSA-163125 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorSecreted |
| Alternative Antibody Names | Anti-Contactin-4 antibodyAnti-Brain-Derived Immunoglobulin Superfamily Protein 2 antibodyAnti-Big-2 antibodyAnti-CNTN4 antibody |
Information sourced from Uniprot.org
