| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CNTD1 (1-120) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CNTD1 |
| Gene ID: |
124817 |
| Uniprot ID: |
CNTD1_HUMAN |
| Immunogen Region: |
1-120 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human CNTD1 (NP_001317151.1). |
| Immunogen Sequence: |
MVKQAENICRQATIQPRDNK RESQNWRALKQQLVNKFTLR LVSCVQLASKLSFRNKIISN ITVLNFLQALGYLHTKEELL ESELDVLKSLNFRINLPTPL AYVETLLEVLGYNGCLVPAM |
| Function | Plays a role in the different steps of crossover formation during meiotic recombination. Participates in the crossover differentiation step of crossover-specific recombination intermediates through its interaction with PRR19. In addition, stimulates crossover formation through the interactions with RFC3 and RFC4 and simultaneously regulates cell-cycle progression through interactions with CDC34 and subsequent ubiquitination of WEE1. May also participates in an active deselection process that destabilizes or removes excess pre-CO intermediates. |
| Protein Name | Cyclin N-Terminal Domain-Containing Protein 1 |
| Cellular Localisation | NucleusCytoplasmChromosomeShuttles Between The Nucleus And Cytoplasm In A Stage-Specific Manner Of Prophase I CellsCo-Localized At Crossover Sites With Prr19 |
| Alternative Antibody Names | Anti-Cyclin N-Terminal Domain-Containing Protein 1 antibodyAnti-CNTD1 antibodyAnti-CNTD antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
