Anti-CNBP antibody (70-170) (STJ117304)

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STJ117304
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Applications:WB/IHC-P/IF/ICC/ELISA
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:500-1:1000
IHC-P:1:50-1:200
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:CNBP
Gene ID:7555
Uniprot ID:CNBP_HUMAN
Immunogen Region:70-170
Immunogen Sequence:CGRGGHIAKDCKEPKREREQ CCYNCGKPGHLARDCDHADE QKCYSCGEFGHIQKDCTKVK CYRCGETGHVAINCSKTSEV NCYRCGESGHLARECTIEAT A
Specificity:A synthetic peptide corresponding to a sequence within amino acids 70-170 of human CNBP (NP_001120668.1).
Tissue Specificity Expressed in the liver, kidney, spleen, testis, lung, muscle and adrenal glands.
Post Translational Modifications Arginine methylation by PRMT1 in the Arg/Gly-rich region impedes RNA binding.
Function Single-stranded DNA-binding protein that preferentially binds to the sterol regulatory element (SRE) sequence 5'-GTGCGGTG-3', and thereby mediates transcriptional repression. Has a role as transactivator of the Myc promoter. Binds single-stranded RNA in a sequence-specific manner. Isoform 1: Binds G-rich elements in target mRNA coding sequences. Prevents G-quadruplex structure formation in vitro, suggesting a role in supporting translation by resolving stable structures on mRNAs. Isoform 2: Binds to RNA. Isoform 4: Binds to RNA. Isoform 5: Binds to RNA. Isoform 6: Binds to RNA. Isoform 8: Binds to RNA.
Protein Name Cchc-Type Zinc Finger Nucleic Acid Binding Protein
Cellular Nucleic Acid-Binding Protein
Cnbp
Zinc Finger Protein 9
Database Links Reactome: R-HSA-9705671
Cellular Localisation Nucleus
Cytoplasm
Endoplasmic Reticulum
Isoform 1: Cytoplasm
Isoform 2: Cytoplasm
Isoform 4: Cytoplasm
Isoform 5: Cytoplasm
Isoform 6: Cytoplasm
Isoform 8: Cytoplasm
Alternative Antibody Names Anti-Cchc-Type Zinc Finger Nucleic Acid Binding Protein antibody
Anti-Cellular Nucleic Acid-Binding Protein antibody
Anti-Cnbp antibody
Anti-Zinc Finger Protein 9 antibody
Anti-CNBP antibody
Anti-RNF163 antibody
Anti-ZNF9 antibody

Information sourced from Uniprot.org