| Short Description : | Mouse monoclonal anti-CMBL (1-245aa) for use in ELISA and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | ELISA/WB |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | AT2B11 |
| Isotype: | IgG2ak |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | By protein-G affinity chromatography |
| Formulation: | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CMBL |
| Gene ID: | 134147 |
| Uniprot ID: | CMBL_HUMAN |
| Accession Number: | NP_620164 |
| Immunogen: | Recombinant human CMBL (1-245aa) purified from E. coli |
| Immunogen Region: | 1-245aa |
| Tissue Specificity | Widely expressed, with highest levels in liver, followed by kidney, small intestine and colon. Present in liver and intestine (at protein level). |
| Function | Cysteine hydrolase. Can convert the prodrug olmesartan medoxomil into its pharmacologically active metabolite olmerstatan, an angiotensin receptor blocker, in liver and intestine. May also activate beta-lactam antibiotics faropenem medoxomil and lenampicillin. |
| Protein Name | Carboxymethylenebutenolidase Homolog |
| Database Links | Reactome: R-HSA-211945 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Carboxymethylenebutenolidase Homolog antibodyAnti-CMBL antibody |
Information sourced from Uniprot.org
