| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CLEC10A |
| Gene ID: | 10462 |
| Uniprot ID: | CLC10_HUMAN |
| Immunogen Region: | 60-180 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-180 of human CD301/CLEC10A (NP_878910.1). |
| Immunogen Sequence: | FQNSKFQRDLVTLRTDFSNF TSNTVAEIQALTSQGSSLEE TIASLKAEVEGFKQERQAGV SELQEHTTQKAHLGHCPHCP SVCVPVHSEMLLRVQQLVQD LKKLTCQVATLNNNASTEGT C |
| Function | Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells. |
| Protein Name | C-Type Lectin Domain Family 10 Member AC-Type Lectin Superfamily Member 14Macrophage Lectin 2Cd Antigen Cd301 |
| Database Links | Reactome: R-HSA-5621480 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-C-Type Lectin Domain Family 10 Member A antibodyAnti-C-Type Lectin Superfamily Member 14 antibodyAnti-Macrophage Lectin 2 antibodyAnti-Cd Antigen Cd301 antibodyAnti-CLEC10A antibodyAnti-CLECSF13 antibodyAnti-CLECSF14 antibodyAnti-HML antibody |
Information sourced from Uniprot.org