Anti-Cleaved-SPTAN1-D1185 antibody (1136-1185 aa) (STJ90073)

SKU:
STJ90073
$67.62 - $360.18
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Short Description :Rabbit polyclonal anti-Cleaved-Spectrin alpha chain, non-erythrocytic 1-D1185 (1136-1185 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/ELISA
Host:Rabbit
Reactivity:Human/Rat/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-1:2000
ELISA 1:10000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:SPTAN1
Gene ID:6709
Uniprot ID:SPTN1_HUMAN
Immunogen:The antiserum was produced against synthesized peptide derived from the human SPTA2 at the amino acid range 1136-1185
Immunogen Region:1136-1185 aa
Specificity:Cleaved-Spectrin Alpha II (D1185) Polyclonal Antibody detects endogenous levels of fragment of activated Spectrin Alpha II protein resulting from cleavage adjacent to D1185.
Function Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.
Protein Name Spectrin Alpha Chain - Non-Erythrocytic 1
Alpha-Ii Spectrin
Fodrin Alpha Chain
Spectrin - Non-Erythroid Alpha Subunit
Database Links Reactome: R-HSA-264870
Reactome: R-HSA-373753
Reactome: R-HSA-375165
Reactome: R-HSA-445095
Reactome: R-HSA-5673001
Reactome: R-HSA-6798695
Reactome: R-HSA-6807878
Reactome: R-HSA-9013420
Reactome: R-HSA-9013424
Reactome: R-HSA-9662360
Reactome: R-HSA-9662361
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Cortex
Expressed Along The Cell Membrane In Podocytes And Presumptive Tubule Cells During Glomerulogenesis And Is Expressed Along Lateral Cell Margins In Tubule Cells
Alternative Antibody Names Anti-Spectrin Alpha Chain - Non-Erythrocytic 1 antibody
Anti-Alpha-Ii Spectrin antibody
Anti-Fodrin Alpha Chain antibody
Anti-Spectrin - Non-Erythroid Alpha Subunit antibody
Anti-SPTAN1 antibody
Anti-NEAS antibody
Anti-SPTA2 antibody

Information sourced from Uniprot.org