| Host: | Rabbit |
| Applications: | WB/IHC |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Cleaved-Matrix metalloproteinase-21-Ser145 (144-145) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC-p 1:50-300 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MMP21 |
| Gene ID: | 118856 |
| Uniprot ID: | MMP21_HUMAN |
| Immunogen Region: | 144-145 |
| Specificity: | This antibody detects endogenous levels of Human, Mouse MMP21 (Cleaved-Ser145, protein was cleaved amino acid sequence between 144-145 ) |
| Immunogen: | Synthesized peptide derived from human MMP21 (Cleaved-Ser145) |
| Post Translational Modifications | The precursor is cleaved by a furin endopeptidase. |
| Function | Plays a specialized role in the generation of left-right asymmetry during embryogenesis. May act as a negative regulator of the NOTCH-signaling pathway. Cleaves alpha-1-antitrypsin. |
| Protein Name | Matrix Metalloproteinase-21Mmp-21 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Matrix Metalloproteinase-21 antibodyAnti-Mmp-21 antibodyAnti-MMP21 antibody |
Information sourced from Uniprot.org