| Short Description : | Rabbit polyclonal anti-Cleaved-Plasma kallikrein-I391 (390-391) for use in WB, ELISA and IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA/IHC |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Dilution Range: | WB 1:500-2000IHC-p 1:50-300ELISA 2000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KLKB1 |
| Gene ID: | 3818 |
| Uniprot ID: | KLKB1_HUMAN |
| Immunogen: | Synthesized peptide derived from human Plasma Kallikrein LC (Cleaved-I391) |
| Immunogen Region: | 390-391 |
| Specificity: | This antibody detects endogenous levels of Human Cleaved-Plasma Kallikrein LC (I391, protein was cleaved amino acid sequence between 390-391 ) |
| Function | Participates in the surface-dependent activation of blood coagulation. Activates, in a reciprocal reaction, coagulation factor XII/F12 after binding to negatively charged surfaces. Releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin. |
| Protein Name | Plasma KallikreinFletcher FactorKininogeninPlasma PrekallikreinPkk Cleaved Into - Plasma Kallikrein Heavy Chain - Plasma Kallikrein Light Chain |
| Database Links | Reactome: R-HSA-140837Reactome: R-HSA-1592389Reactome: R-HSA-9657688Reactome: R-HSA-9657689 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Plasma Kallikrein antibodyAnti-Fletcher Factor antibodyAnti-Kininogenin antibodyAnti-Plasma Prekallikrein antibodyAnti-Pkk Cleaved Into - Plasma Kallikrein Heavy Chain - Plasma Kallikrein Light Chain antibodyAnti-KLKB1 antibodyAnti-KLK3 antibody |
Information sourced from Uniprot.org
