| Short Description : | Rabbit polyclonal anti-Cleaved-Eosinophil peroxidase-Val251, Heavy Chain (250-251) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Dilution Range: | WB 1:1000-2000ELISA 1:5000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EPX |
| Gene ID: | 8288 |
| Uniprot ID: | PERE_HUMAN |
| Immunogen: | Synthesized peptide derived from human Eosinophil peroxidase (heavy chain, Cleaved-Val251) |
| Immunogen Region: | 250-251 |
| Specificity: | This antibody detects endogenous levels of Human, Mouse, Rat Eosinophil peroxidase (heavy chain, Cleaved-Val251, protein was cleaved amino acid sequence between 250-251 ) |
| Function | Mediates tyrosine nitration of secondary granule proteins in mature resting eosinophils. Shows significant inhibitory activity towards Mycobacterium tuberculosis H37Rv by inducing bacterial fragmentation and lysis. |
| Protein Name | Eosinophil PeroxidaseEpo Cleaved Into - Eosinophil Peroxidase Light Chain - Eosinophil Peroxidase Heavy Chain |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Cytoplasmic GranuleCytoplasmic Granules Of Eosinophils |
| Alternative Antibody Names | Anti-Eosinophil Peroxidase antibodyAnti-Epo Cleaved Into - Eosinophil Peroxidase Light Chain - Eosinophil Peroxidase Heavy Chain antibodyAnti-EPX antibodyAnti-EPER antibodyAnti-EPO antibodyAnti-EPP antibody |
Information sourced from Uniprot.org
