Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Claudin-4 (160-209 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:5000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
CLDN4 |
Gene ID: |
1364 |
Uniprot ID: |
CLD4_HUMAN |
Immunogen Region: |
160-209 aa |
Specificity: |
Claudin-4 Polyclonal Antibody detects endogenous levels of Claudin-4 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human Claudin 4 at the amino acid range 160-209 |
Function | Channel-forming tight junction protein that mediates paracellular chloride transport in the kidney. Plays a critical role in the paracellular reabsorption of filtered chloride in the kidney collecting ducts. Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. |
Protein Name | Claudin-4Clostridium Perfringens Enterotoxin ReceptorCpe-RCpe-ReceptorWilliams-Beuren Syndrome Chromosomal Region 8 Protein |
Database Links | Reactome: R-HSA-420029 |
Cellular Localisation | Cell JunctionTight JunctionCell MembraneMulti-Pass Membrane ProteinCldn4 Is Required For Tight Junction Localization In The Kidney |
Alternative Antibody Names | Anti-Claudin-4 antibodyAnti-Clostridium Perfringens Enterotoxin Receptor antibodyAnti-Cpe-R antibodyAnti-Cpe-Receptor antibodyAnti-Williams-Beuren Syndrome Chromosomal Region 8 Protein antibodyAnti-CLDN4 antibodyAnti-CPER antibodyAnti-CPETR1 antibodyAnti-WBSCR8 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance