| Short Description : | Rabbit polyclonal anti-H+/Cl-exchange transporter 6 (611-660 aa) for use in WB and ELISA in Human, Mouse, Rat and Monkey samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat/Monkey |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000ELISA 1:40000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CLCN6 |
| Gene ID: | 1185 |
| Uniprot ID: | CLCN6_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human CLCN6 at the amino acid range 611-660 |
| Immunogen Region: | 611-660 aa |
| Specificity: | CLC-6 Polyclonal Antibody detects endogenous levels of CLC-6 protein. |
| Post Translational Modifications | N-glycosylated on several asparagine residues. |
| Function | Voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the late endosome lumen. The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons. The presence of conserved gating glutamate residues is typical for family members that function as antiporters. |
| Protein Name | H(+/Cl(- Exchange Transporter 6Chloride Channel Protein 6Clc-6Chloride Transport Protein 6 |
| Database Links | Reactome: R-HSA-2672351Reactome: R-HSA-6802952 |
| Cellular Localisation | Late Endosome MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-H(+/Cl(- Exchange Transporter 6 antibodyAnti-Chloride Channel Protein 6 antibodyAnti-Clc-6 antibodyAnti-Chloride Transport Protein 6 antibodyAnti-CLCN6 antibodyAnti-KIAA0046 antibody |
Information sourced from Uniprot.org
