| Function | Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors. The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. CIAO1:CIAO2A specifically matures ACO1 and stabilizes IREB2. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation. |
| Protein Name | Probable Cytosolic Iron-Sulfur Protein Assembly Protein Ciao1Wd Repeat-Containing Protein 39 |
| Database Links | Reactome: R-HSA-2564830 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Probable Cytosolic Iron-Sulfur Protein Assembly Protein Ciao1 antibodyAnti-Wd Repeat-Containing Protein 39 antibodyAnti-CIAO1 antibodyAnti-CIA1 antibodyAnti-WDR39 antibody |
Information sourced from Uniprot.org
