| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-nAChR b4 (Cytoplasmic Loop) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol. |
| Purification: | This antibody was antigen affinity purified from pooled serum. |
| Dilution Range: | WB 1:1000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | Chrnb4 |
| Gene ID: | 108015 |
| Uniprot ID: | ACHB4_MOUSE |
| Immunogen Region: | Cytoplasmic Loop |
| Immunogen: | Fusion protein from the cytoplasmic loop of the beta 4 subunit of rat nAChR. |
| Tissue Specificity | Predominantly expressed by immature T-cells in the thymus. |
| Function | After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. |
| Protein Name | Neuronal Acetylcholine Receptor Subunit Beta-4 |
| Database Links | Reactome: R-MMU-629587Reactome: -MMU-629594Reactome: -MMU-629597Reactome: -MMU-6798695 |
| Cellular Localisation | Postsynaptic Cell MembraneMulti-Pass Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Neuronal Acetylcholine Receptor Subunit Beta-4 antibodyAnti-Chrnb4 antibodyAnti-Acrb4 antibody |
Information sourced from Uniprot.org
