• Western blot of mouse forebrain lysates from Wild Type (WT) and Alpha 6-knockout (K/O) animals showing specific immunolabeling of the ~57 kDa Alpha 6-subunit of the GABAA-R. The labeling was absent from a lysate prepared from Alpha 6-knockout animals.

Anti-GABRA6 antibody (Cytoplasmic Loop) (STJA0003644)

SKU:
STJA0003644-100

£442.50
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Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-GABAA Receptor a 6 (Cytoplasmic Loop) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol.
Purification: This antibody was antigen affinity purified from serum.
Dilution Range: WB 1:1000
IHC
ICC
IP
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: Gabra6
Gene ID: 29708
Uniprot ID: GBRA6_RAT
Immunogen Region: Cytoplasmic Loop
Immunogen: Fusion protein from the cytoplasmic loop of the alpha 6 subunit.
Tissue Specificity Only found in cerebellar granule cells.
Function GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Protein Name Gamma-Aminobutyric Acid Receptor Subunit Alpha-6
Gaba(A Receptor Subunit Alpha-6
Database Links Reactome: R-RNO-977443
Cellular Localisation Postsynaptic Cell Membrane
Multi-Pass Membrane Protein
Cell Membrane
Alternative Antibody Names Anti-Gamma-Aminobutyric Acid Receptor Subunit Alpha-6 antibody
Anti-Gaba(A Receptor Subunit Alpha-6 antibody
Anti-Gabra6 antibody
Anti-Gabra-6 antibody

Information sourced from Uniprot.org

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