Host: | Mouse |
Applications: | FC |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Mouse monoclonal antibody anti-Acetylcholine Receptor Subunit Alpha is suitable for use in Flow Cytometry research applications. |
Clonality : | Monoclonal |
Clone ID : | Mab35 |
Conjugation: | Unconjugated |
Isotype: | IgG1k |
Formulation: | 0.01M PBS, pH 7.4. |
Purification: | Protein A/G purified from cell culture supernatant. |
Concentration: | 1 mg/ml |
Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Gene Symbol: | CHRNA1 |
Gene ID: | 1134 |
Uniprot ID: | ACHA_HUMAN |
Function | Isoform 1: Upon acetylcholine binding, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Isoform 2: Non functional acetylcholine receptor alpha subunit which is not integrated into functional acetylcholine-gated cation-selective channels. |
Protein Name | Acetylcholine Receptor Subunit Alpha |
Database Links | Reactome: R-HSA-629594Reactome: R-HSA-629597 |
Cellular Localisation | Postsynaptic Cell MembraneMulti-Pass Membrane ProteinCell Membrane |
Alternative Antibody Names | Anti-Acetylcholine Receptor Subunit Alpha antibodyAnti-CHRNA1 antibodyAnti-ACHRA antibodyAnti-CHNRA antibody |
Information sourced from Uniprot.org