| Host: | Mouse |
| Applications: | FC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-Acetylcholine Receptor Subunit Alpha for use in FC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | Mab35 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1k |
| Formulation: | 0.01M PBS, pH 7.4. |
| Purification: | Protein A/G purified from cell culture supernatant. |
| Concentration: | 1 mg/ml |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Gene Symbol: | CHRNA1 |
| Gene ID: | 1134 |
| Uniprot ID: | ACHA_HUMAN |
| Function | Isoform 1: Upon acetylcholine binding, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Isoform 2: Non functional acetylcholine receptor alpha subunit which is not integrated into functional acetylcholine-gated cation-selective channels. |
| Protein Name | Acetylcholine Receptor Subunit Alpha |
| Database Links | Reactome: R-HSA-629594Reactome: R-HSA-629597 |
| Cellular Localisation | Postsynaptic Cell MembraneMulti-Pass Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Acetylcholine Receptor Subunit Alpha antibodyAnti-CHRNA1 antibodyAnti-ACHRA antibodyAnti-CHNRA antibody |
Information sourced from Uniprot.org